Peer Review Report for 10.1105/tpc.17.00186 A Regulatory Hierarchy of the Arabidopsis Branched-chain Amino Acid Metabolic Network

All reviewers recognized the importance of the results described in this study; however, each requested additional discussion of particular points raised in the manuscript. Reviewer 3 in particular raised three important aspects that require further discussion, and had good editorial suggestions for streamlining the Results section for improved clarity. Reviewer 3 also pointed out that data in Fig 7, 11, and Supplemental Table 6 require different statistical treatment than a t-test. Consider an improved pathway figure per reviewer 2 and additional clarification to figures and text suggested by reviewer 3.